Problems with intestinal functionality sooner or later are observed in almost every person. The reasons for such failures are numerous, and the accompanying symptoms can be very unpleasant. To fix the problem, a variety of methods can be used, from simple correction of the menu and diet to taking pills to improve metabolism and restore digestion. Consider the factors causing the failure, the signs that accompany it, and the drugs used for treatment.

Causes of disturbances in digestive processes

Deterioration of digestion can be observed in the background various diseases, and then it is impossible to fix the failure without identifying the root cause. However, much more often the victim himself is to blame for his own troubles, not wanting to lead a correct lifestyle and violating the rules of competent nutrition.

Failure can occur as a result of:

• Abuse of fatty and spicy foods, smoked meats, sweets and other indigestible and saturated simple carbohydrates.
• Overeating, which is often observed with hasty absorption of food. The stomach, filling up too quickly, does not have time to transmit the necessary information to the brain in time, hence the erroneous feeling of hunger.
• Snacks on the run, as a result of which food is not chewed sufficiently and as a result is difficult to digest.
• Late meals, because in the evening all processes in the body slow down. Accordingly, once in the stomach after 21.00, food may not be digested at all.

Another problem is the incorrectly constructed drinking circuit. Nutritionists are absolutely right in recommending drinking a lot of water, but this should be done wisely, since it is unacceptable to drink during a meal, immediately before or after it. The problem lies in the dilution of enzymes, which worsens their effect and does not contribute to high-quality digestion of food.

Signs of a malfunctioning digestive system

In cases where the work of the gastrointestinal tract is disrupted, very eloquent symptoms appear, indicating the need to take medication for digestion.

Suspicious symptoms include:

• Unpleasant sensations in the intestinal region, the presence of a constant upset stool, manifested in constipation or diarrhea, the appearance of nausea, flatulence and bloating.
• Stomach pain occurs, most often after eating.
• Decreases or completely disappears appetite, which indicates the progression of the painful condition.
• Impaired digestive system functionality leads to insufficient intestinal absorption essential vitamins, minerals and other useful elements, which leads to the consumption of their own reserves. The result is constant fatigue, bad mood, drowsiness.
• Due to the lack of important components, it deteriorates appearance - there is a drying out of the skin, the appearance of pigmentation and scars on it, the hair splits, weakens and loses its shine, the nail plates break and exfoliate.

Even one of the listed signs is enough to show anxiety, and if there are several of them, you need to immediately go to the clinic for an examination.

Types of preparations for stabilizing digestive processes

When the work of the digestive system is disturbed, the disturbance is corrected by developing supportive actions necessary when eating.

They change the diet, adjust the menu, prescribe special medications, which are divided into three types, taking into account the main active element:

• Preparations based on Pancreatin... These food digestion pills are considered the most effective in terms of both effect and time to achieve. Pancreatin is a digestive enzyme that, when taken, starts working just minutes later, eliminating indigestion.
• Preparations with Pancreatin and Supplements... In addition to the main component, bile acids have a positive effect, cellulose and other substances are also included in the composition. They accelerate the breakdown of complex carbohydrates and normalize bowel function while increasing the production of digestive enzymes.
• Drugs that restore the normal functioning of the pancreas.

Only an experienced specialist can determine which group of drugs will have the required effect. It should be understood that different pathologies can be accompanied by very similar symptoms. Accordingly, in certain situations, it is more advisable to choose a medicine with additional components.

Forms of medicines

An important point is the rate of action of the drug, which depends on its form.

The modern pharmaceutical industry produces digestive enzymes in two versions, these can be:

• More familiar pills, the action of which is focused only on the normalization of the stomach.
• Capsules that have appeared in pharmacies relatively recently. The enzymes produced in this form are more effective, which has been proven in clinical studies. The main advantage of capsules when compared to tablets is the simultaneous effect on both the stomach and intestines. This effect is achieved thanks to a special shell that dissolves gradually, so some of the substance remains in the stomach, and the remainder penetrates directly into the intestines.

In cases where the discomfort is determined exclusively in the stomach, there is no need to take more expensive capsules.

Features of pancreatin

Consider pills to normalize digestion and start with effective means -. From a number of enzymes, it is distinguished not only by a strong and quick effect, but also by its affordable cost.

The drug is prescribed for:

• insufficient production of pancreatic enzymes;
• long-term disorders in the functionality of the stomach and intestines, liver;
• inactive lifestyle;
• overeating;
• difficulties affecting chewing processes.

The drug does not have strictly established dosages, it is normally recommended to drink one tablet with food. If there is an acute course of the pathology, it is advisable to increase the dosage at each intake to two tablets. In this case, the side effects of the drug are almost completely absent and can be observed in 1% of patients. Among the negative phenomena are discomfort in the stomach, nausea and vomiting, allergic rash, increased volume uric acid.

Other drugs

In addition to Pancreatin, the most sought-after drugs include:

• ... Release form - capsules. The drug is prescribed for chronic pancreatitis, stomach oncology, overeating, treatment after surgical interventions affecting the gastrointestinal tract.
• Mezim... Release form - tablets designed to improve the functionality of the digestive system. The tool helps with a lack of enzymes, problems with metabolic processes, inflammation affecting the mucous membranes of the gastric layers, chronic pancreatitis. The drug has a number of contraindications, it is not prescribed in case of intestinal obstruction and hepatitis.
• Festal... The product contains a number of components that help in the absorption of fiber, lipase activation, normalization of the absorption of the necessary elements. The remedy is indicated for diarrhea that did not occur against the background of infectious intestinal pathologies, insufficient production of pancreatic enzymes, the presence of flatulence, irritation of the intestinal walls, abuse of spicy, fatty or salty foods. The drug should be limited in acute pancreatitis, hepatitis, allergies, intestinal obstruction, diabetes mellitus.
• Enzistal... Restores the functionality of the digestive tract. The remedy is taken with a lack of enzymes, flatulence, problems with chewing processes, an insufficiently active lifestyle. With caution, the remedy is prescribed for jaundice, the presence of hepatic or renal failure, intestinal obstruction.

Somilase can also be prescribed, which has a positive effect on the digestive system and pancreas. The tool breaks down fats, while making up for the lack of enzymes. The main purpose is the presence of chronic pancreatitis and gastritis in acute form, inflammatory processes occurring in the large or small intestine.

Digestive enzymes Are biologically active substances, the main purpose of which is to aid in the digestion of food. They are able to enter into chemical interaction with the structures of proteins, fats and carbohydrates, breaking them down to compounds available for absorption. In the human body, they are produced at almost all stages of digestion, but sometimes they are not enough and additional support from the outside is required as medicines.

There are several types of digestive enzymes, each of which is capable of breaking down a specific compound:

List of enzyme preparations

Enzyme preparations are also usually divided into groups, depending on the main active ingredient and the composition of the drug:

1. Pancreatin-containing preparations: Pancreatin, Mezim-forte, Penzital, Pangrol, Creon and others.
2. Complex enzyme preparations. In addition to pancreatin, the composition contains bile, hemicellulase, pancran, enzistal and others.
3. Lipolytic combined drugs: Somilaza, Solizim and others.

Pancreatin

Popular, affordable drug. The main purpose is the breakdown of protein foods. Indications for use are:

Mezim

In addition to pancreatin, the preparation contains enzymes and lipase. Acts more mildly than pancreatin, it is approved for use even for children. The drug Mezim-forte 10000 is similar to pancreatin.

Indications for use are almost the same as for pancreatin. It refers not to therapeutic, but to prophylactic drugs intended to prevent and prevent further aggravation of the condition in such diseases as: chronic pancreatitis, gastroduodenitis, cholecystitis. The main point of application is overeating and functional indigestion.

Penzinal

The drug is analogous to pancreatin, but contains more active enzymes. Recommended for the treatment of acute conditions:

• acute pancreatitis and pancreatic necrosis;
• condition after removal of the gallbladder;
• condition after resection of the stomach, intestines;
• a period of dehydration that lasted a long time, etc.

Micrasim

Capsule drug that dissolves at the intestinal level. The gastric juice does not affect the capsule, and it passes in transit to, where, under the action of the intestinal juice, the active substances are released.

Used when:

Creon

A drug, the main advantage of which is a capsule capable of partial release of enzymes. The capsule dissolves in the stomach, the microgranules have an enteric shell, therefore they penetrate unchanged into the intestine, where the drug begins its work, moving further along with the chyme.

Main purpose:

• cystic fibrosis, the best solution in childhood;
• pancreatic necrosis;
• removal of a part of the pancreas with severe enzymatic deficiency;
• oncopathology of the gastrointestinal tract;
• schwachman-diamond disease and others.

Somilaza

The preparation contains two enzymes: lipolytic solizyme and alpha-amylase. All ingredients are derived from plants. The drug is indicated exclusively for violation of the pancreas associated with insufficient lipolysis. It can be used in case of violation of the diet and excessive consumption of fatty foods to facilitate digestion.

Often causes allergic reactions due to the presence of herbal ingredients. Unlike the previous names, which are taken with food, the drug must be taken after meals.

Enzistal

The combined preparation contains bile components in the composition, thereby increasing the activity of its own enzymes. Found the main application in chronic cholecystitis, gallstone disease, hepatitis, cholangitis and after removal of the gallbladder - with insufficient digestion and bile deficiency.

It is taken after meals. May cause nausea and even vomiting in case of drug overdose.

When are enzymes prescribed?

Pancreatic enzymes are far from harmless drugs. Their prescription should be supervised by general practitioners or gastroenterologists. The main indications for which their appointment is necessary:

• insufficiency of the pancreas due to inflammatory diseases of various etiologies (autoimmune, alcoholic, pancreatic necrosis, after dietary disorders, and so on), oncological processes and resection of the gland;
• inflammatory diseases of the gastric and intestinal mucosa to improve food digestion and facilitate absorption;
• with bile insufficiency in inflammatory diseases of the liver, its ducts, gallbladder, as well as after operations to remove the bladder and resection of the liver;
• single or short-term use for functional digestive disorders (after dietary disorders - loose stools, heartburn, nausea) and overeating.

Contraindications

Enzymes have their own contraindications, especially in the presence of plant or animal ingredients:

Is enzyme use justified or can it be avoided?

Enzyme preparations should be prescribed strictly according to indications. Excessive addiction to drugs of this pharmacological group leads to a significant decrease in the function of the pancreas itself and even sometimes to atrophy of the gastric mucosa and cells that secrete enzymes as they are unnecessary.

In a serious condition of the patient, with insufficient digestion and poor absorption, replacement therapy is necessary. With insufficient digestion, cachexia can develop with normal appetite and good nutrition, but also significant vitamin deficiencies.

Depending on the pathology, the doctor calculates the dosage and indicates the duration of the intake. Sometimes after prolonged use, it is recommended to gradually withdraw the drug over several days or weeks. The pancreas is then activated for normal operation after unloading.

Basic recommendations for improving enzymatic activity

• Proper nutrition. This concept includes not only dietary products, but also a rational regimen (eating at a strictly regulated time, at least three times a day, in the same portions).
• An active lifestyle. Sport improves intestinal motility, increases the tone of the bile and pancreatic ducts, improving the evacuation of secretions.
• Increase the consumption of clean water to 2-2.5 liters. It promotes better dissolution of compounds and facilitates absorption, softens the chyme and facilitates its movement along the intestinal tube.
• Chew food slowly. In ancient Japan, samurai chewed a portion of rice, calculating 40 chewing movements. Well-mechanically processed food is easier to digest, saliva enzymes have time to break down more compounds, making further work easier.

See also vigeratin, cholenzyme.

ABOMIN (Abominum)

The drug obtained from the gastric mucosa of calves and lambs of milk age; contains the sum of proteolytic (protein-breaking) enzymes.

Pharmachologic effect. Possesses proteolytic activity.

Indications for use. Diseases of the gastrointestinal tract, accompanied by impaired digestion and a decrease in the acidity of gastric juice: gastritis (inflammation of the gastric mucosa), gastroenteritis (inflammation of the mucous membranes

membranes of the stomach and small intestine), enterocolitis (combined inflammation of the small and large intestine), etc.

Method of administration and dosage. Inside with meals, 1 tablet 3 times a day for 1-2 months; with insufficient effectiveness, a single dose is increased to 3 tablets, and the course of treatment is extended to 3 months. For acute gastritis, gastroenteritis, colitis, 1 tablet is prescribed 3 times a day for 2-3 days.

Side effect. IN individual cases mild nausea, heartburn.

Contraindications. Obstruction of the gastrointestinal tract,

Release form. Tablets of 50,000 U, in a package of 10 pieces.

Storage conditions. In a cool dry place, protected from light.

ALPHA-AMILASE (Alpha-amilase)

Pharmachologic effect. Algalolytic (decomposing starch, glycogen and related compounds) enzyme. Optimizes the digestion of carbohydrates.

Indications for use. Lack of pancreatic function, inadequate digestion; operations on the pancreas, intestines, liver and stomach.

Method of administration and dosage. The dose is selected individually. Used in conjunction with other enzymes inside during or after meals.

Release form. Powder.

Storage conditions. In a dry place at temperatures from 0 to +5 "C.

VESTAL (Vestalum)

Pharmachologic effect. Complex enzyme preparation that stimulates digestion.

Indications for use. Insufficient secretory (insufficient secretion of digestive juices) and digestion capacity of the gastrointestinal tract, digestive disorders associated with a violation of diet or overeating, gastritis (inflammation of the stomach), pancreatitis (inflammation of the pancreas), hepatitis (inflammation of the liver tissue), cholecystitis (inflammation of the bile bubble), etc.

Method of administration and dosage. Inside, 1-3 tablets with meals or immediately after meals 3 times a day.

Release form. Film-coated tablets, pack of 50.

Storage conditions. In a cool place.

NATURAL GASTRIC JUICE (Succusgastricusnaturalis)

Gastric secretion (gastric juice) of healthy dogs and other domestic animals, canned with 0.03-0.04% salicylic acid.

Indications for use. With insufficient function of the gastric glands, achilia (lack of secretion in the stomach of hydrochloric acid and enzymes), hypoanacid gastritis (inflammation of the stomach, accompanied by a decrease in the level or absence of hydrochloric acid), dyspepsia (indigestion).

Method of administration and dosage. Assign inside during or after meals 2-3 times a day for 1-2 tablespoons (children, depending on age, from "/ 2 teaspoon to 1 tablespoon).

Release form. Natural juice from dogs in bottles of 100 ml. Natural juice from equine horses - in bottles of 100 ml.

Storage conditions. In a dark place at a temperature of +2 to +10 ° C.

LACTRASE (Lactrase)

Synonyms: Trilactase.

Pharmachologic effect. A digestive enzyme, which is lactase (disaccharidase), which is located in the alkaline border of the mucous membrane of the jejunum and the proximal (initial) part of the ileum (part of the small intestine). During digestion, it breaks down lactose into simple sugars (galactose and glucose), which are absorbed in the intestines.

Indications for use. Lactase deficiency of varying severity (hypolactasia, analactasia).

Method of administration and dosage. Assign inside 250-500 mg before drinking milk or dairy products. Increase the dose if necessary. In patients with diabetes mellitus the need for lactrase is determined by the doctor. It should be borne in mind that from 2 liters of milk when lactose is broken down, 25 g of glucose and 25 g of galactose are formed.

The drug can be added to food containing lactose. To do this, pour the contents of the capsule into the finished dish. The drug can be added to milk in advance by dissolving the contents of 1-2 capsules in 1 liter of milk, stirring and refrigerating for 24 hours.

Side effect. Rarely - a feeling of discomfort in the epigastrium (the area of \u200b\u200bthe abdomen located directly under the place of convergence of the rib and sternum)

Contraindications. Hypersensitivity to the drug.

Release form. 250 mg capsules in a package of 10 and 30 pieces.

Storage conditions. Store in a cool dry place.

NIGEDASA

The drug was isolated from the seeds of damask (Nigelladamascena).

Pharmachologic effect. An enzyme of lipolytic action (decomposing fats), causes the hydrolytic breakdown (decomposition with the participation of water) of vegetable and animal fats.

Indications for use. To compensate for the missing or absent lipolytic activity of duodenal juice (digestive juices secreted by the duodenum) caused by pathology (disease) of the digestive system (pancreatitis - inflammation of the pancreas, cholecystopancreatitis - concomitant inflammation of the gallbladder tissue and chronic hepatitis - chronic hepatitis gastritis - inflammation of the gastric mucosa; enterocolitis - inflammation of the small and large intestine, etc.).

Method of administration and dosage. Inside, 1-2 tablets for 10-30 minutes. before meals, washed down with water, with achilia (absence of secretion in the stomach of hydrochloric acid and enzymes), hypo- and anacid conditions (decrease in the level or absence of hydrochloric acid in the stomach) - 1-2 tablespoons of natural gastric juice. The course of treatment is 3-4 weeks, if necessary, it can be longer.

Side effect. People with chronic colitis (inflammation of the colon) may experience abdominal pain, which disappears when the dose is reduced.

Release form. Tablets of 0.15 g, soluble in the intestine, in a package of 30 pieces.

Storage conditions. At a temperature not higher than +10 ° С,

ORAZA (Orazum)

Pharmachologic effect. An acid-resistant complex of amylolytic (degrading polysaccharides) and proteolytic (degrading proteins) enzymes, facilitating the digestion of basic nutrients.

Indications for use. Gastritis (inflammation of the gastric mucosa) with low acidity, chronic hepatocholecystitis (concomitant inflammation of the liver and biliary tract tissues), gastric ulcer with decreased secretion (with decreased production of gastric juice), subacute and chronic pancreatitis (inflammation of the pancreas).

chronic spastic colitis (inflammation of the colon, characterized by sharp painful contractions) with a tendency to constipation.

Method of administration and dosage. Inside, 1 / 2-1 teaspoon during or immediately after meals 3 times a day. The course of treatment is 2-4 weeks.

Side effect. Patients with diarrhea (diarrhea) may have increased diarrhea.

Release form. Granules in jars of 100 g.

Storage conditions. Store in a cool dry place.

PANCREATIN (Pancreatinum)

Synonyms: Pancitrate.

Pharmachologic effect. The pancreatic enzymes (pancreatic enzymes) included in the preparation - amylase, lipase and protease - facilitate the digestion of carbohydrates, fats and proteins, which contributes to their more complete absorption in the small intestine. In diseases of the pancreas, the drug compensates for the insufficiency of its secretory function (secretion of digestive juice) and helps to improve the digestion process.

Indications for use. Insufficiency of the secretory function of the pancreas (chronic pancreatitis - inflammation of the pancreas, cystic fibrosis - a hereditary disease characterized by blockage of the outlet ducts of the pancreas, glands respiratory tract and intestines, viscous secretions, etc.). Chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gallbladder; conditions after resection (removal of part of an organ) or irradiation of these organs, accompanied by impaired digestion of food, flatulence (accumulation of gases in the intestine), diarrhea (diarrhea) - as part of combination therapy. Condition after pancreatectomy (removal of the pancreas). Obstruction (obstruction) of the pancreatic ducts or biliary tract. To improve digestion, write in patients with normal function of the gastrointestinal tract in case of a violation of the diet, as well as in violation of the chewing function, forced prolonged immobilization (immobilization), a sedentary lifestyle. Preparation for X-ray and ultrasound examination of the abdominal organs.

Method of administration and dosage. The dose of the drug (in terms of lipase) depends on the age and degree of pancreatic insufficiency. The average dose for adults is 150,000 U / day. With complete insufficiency of the secretory function of the pancreas - 400,000 U / day, which corresponds to the daily requirement of an adult for lipase. The maximum daily dose is 15 GOO-20,000 U / kg body weight.

Children under the age of 1.5 years are prescribed 50,000 U / day; over 1.5 years - 100,000 U / day.

In cystic fibrosis, the dose of the drug is selected individually. The dose should be adequate to the amount of enzymes needed to absorb fat, taking into account the quality and quantity of food consumed.

Tablets, capsules or pills are taken with meals, swallowed whole, washed down with a large amount of non-alkaline liquid (water, fruit juices). To facilitate swallowing and improve the absorption of the drug used in capsules, especially in patients after gastric resection, you can open the capsule and swallow its contents without chewing.

The duration of treatment can vary from several days (in case of indigestion due to inaccuracies in the diet) to several months or even years (if constant substitution therapy is necessary).

Side effect.Acute pancreatitis (inflammation of the pancreas). With prolonged use, hypersensitivity reactions are very rare. In some cases, there are immediate allergic reactions, as well as allergic reactions from the digestive tract. With prolonged use of high doses of the drug, the development of hyperuricosuria (increased content of uric acid in the urine) is possible. With cystic fibrosis, after taking large doses, sometimes there is the formation of strictures (narrowings) in the ileocecal section (the junction of the large and small intestines) and in the colon (section of the large intestine).

Contraindications. Acute pancreatitis, exacerbation of chronic pancreatitis, hypersensitivity to drug components.

Release form. Pills. Capsules. Dragee. Gelatin capsules containing enteric-coated microtablets containing lipase 10,000, 20,000 or 25,000 units each; amylase at 9000, 18000 or 22,500 units; protease 500, 1000 or 1250 units.

Storage conditions. Store in a cool dry place.

Vobenzmuin

Pharmachologic effect. Complex enzyme preparation that improves digestion.

Indications for use. Digestive disorders, insufficiency of secretory function (secretion of digestive juices) of the pancreas, gallbladder, liver, pancreatitis (inflammation of the pancreas), etc.

Method of administration and dosage. Inside, 1 tablet 3 times a day with meals with a little water.

Side effects and contraindications are the same as for the drug pangrol 400 (see? Tr. 346).

Release form. Film-coated tablets in a pack of 20 or 50 pieces. 1 tablet contains: pancreatin - 0.1 g, papain - 0.06 g, bromelin - 0.045 g, lipase - 0.01 g, trypsin - 0.024 g, chymotrypsin - 0.0001 g, rutin - 0.05 g.

Storage conditions. Store in a cool dry place.

MEZIM-FORTE (Mezym-forte)

Pharmachologic effect. Provides good digestibility of fats, proteins and carbohydrates.

Indications for use. With insufficient secretory (insufficient formation of digestive juices) and digestive capacity of the stomach and intestines (with chronic gastritis - inflammation of the gastric mucosa, enterocolitis - a combination of inflammation of the small and large intestine, etc.), with chronic pancreatitis (inflammation of the pancreas), hepatitis (inflammation liver tissue), cholecystitis (inflammation of the gallbladder).

Method of administration and dosage. Assign to adults 1-3 tablets a day (write before taking).

Release form. Coated dragee, pack of 20. Composition: 140 mg pancreatin, 4200 IU of amylase, 3500 IU of lipase and 250 IU of proteases.

Storage conditions. Regular.

PANGROL 400 (Pangrolum400)

Pharmachologic effect. Enzyme preparation. Normalizes digestion.

Indications for use. Digestive disorders with insufficient function of the pancreas (chronic pancreatitis - inflammation of the pancreas, fibrosis - proliferation of connective tissue

pancreas), resection (removal of part of an organ) of the stomach or small intestine, accelerated passage of food through the intestine, flatulence (accumulation of gas in the intestine).

Method of administration and dosage. Inside before or during meals, 1-2 tablets.

Side effect. In rare cases, diarrhea (diarrhea) is possible.

Contraindications. Hepatitis (inflammation of the liver tissue), obstructive jaundice (jaundice associated with mechanical obstruction of the outflow of bile along the biliary tract), intestinal obstruction, hypersensitivity to the drug.

Release form. Film-coated tablets containing pancreatin with an amylase activity of 12,000 units, lipase 16,000 units and proteinases 720 units of 0.4 g each.

Storage conditions. Store in a cool dry place.

PANZINORMFORTE (Panzinorm forte)

Pharmachologic effect. Replaces enzymes in the stomach and pancreas and stimulates their secretion.

Indications for use. Indigestion of various origins, hypofunction (decreased function) of the pancreas, atrophic gastritis (inflammation of the stomach with thinning of the mucous membrane), gastroduodenitis (inflammation of the stomach and duodenum), hepatitis (inflammation of the liver tissue), cholecystitis (inflammation of the gallbladder), after surgery gastrointestinal tract, pancreas and liver.

Method of administration and dosage. Inside, 1 tablet with meals 3 times a day.

Side effects and contraindications are the same as for pangrol 400.

Release form. Tablets in a package of 30 pieces. Composition of 1 tablet: extract of the gastric mucosa - 200 mg (corresponds to 200 mg of pepsin), dry extract of bile of cattle - 30 mg, pancreatin - 200 mg. The outer shell of the tablet contains an extract of the gastric mucosa, which is released in the stomach; the core of the tablet, containing pancreatin and bile, disintegrates in the duodenum.

Storage conditions. In a cool place.

Pancurmen

Pharmachologic effect.Combined drug. The digestive enzymes included in its composition facilitate the digestion of proteins, fats, carbohydrates, which contributes to their more complete absorption in the small intestine. The extract of turmeric, which is part of the drug, has a choleretic (enhances the formation of bile) and weak cholekinetic (facilitates the secretion of bile into the intestine) effect. Bile promotes emulsification of fats, increases lipase activity, improves the absorption of fats and fat-soluble vitamins A, E, K. The use of the drug leads to an improvement in the functional state of the gastrointestinal tract, normalization of digestion.

Indications for use. Insufficiency of exocrine function (secretion of digestive enzymes) of the pancreas: chronic pancreatitis (in "puffiness of the pancreas), cystic fibrosis (congenital disease, manifested by chronic pneumonia and digestive disorders), etc. Chronic inflammatory-dystrophic diseases of the stomach, gall, liver; conditions after resection (removal of part of an organ) or irradiation of these organs, accompanied by impaired digestion of food, flatulence (accumulation of gases in the intestine), diarrhea (as part of a combination therapy). To improve food digestion in patients with normal function of the gastrointestinal tract in case of errors in nutrition, as well as in violation of chewing function, forced prolonged immobilization (immobilization), a sedentary lifestyle Preparation for X-ray and ultrasound examination of the abdominal organs.

Method of administration and dosage. Assign 2-4 pills 3 times a day before meals or during meals. Dragee should be swallowed whole, without chewing and drinking a small amount of liquid. The duration of treatment can vary from several days (in case of indigestion due to inaccuracies in nutrition) to several months or even years (if constant replacement therapy is necessary).

Side effect. In rare cases, diarrhea (diarrhea) and nausea are possible.

Contraindications. Hepatitis (inflammation of the liver tissue), obstructive jaundice (jaundice associated with mechanical obstruction of the outflow of bile through the biliary tract), intestinal obstruction, hypersensitivity to the drug.

Release form. Film-coated tablets, 20 pieces per pack. 1 tablet contains 0.035 g of pancreatin (amylase 1050 U FIP, lipase 875 U FIP, protease 63 U FIP) and 0.0085 g turmeric extract.

Storage conditions. In a dry, dark place.

PANSTAL (Panstalum)

Pharmachologic effect. A complex enzyme preparation that promotes digestion.

Indications for use. Digestive disorders associated with diseases of the duodenum and gallbladder, gastroenteritis (inflammation of the mucous membranes of the stomach and small intestine), flatulence (accumulation of gas in the intestine) after cholecystectomy (removal of the gallbladder), taking fatty food, during the adaptation period after dental prosthetics.

Method of administration and dosage. Inside, 1-2 tablets 3 times a day during or immediately after meals.

Contraindications. Acute liver disease, hepatic coma, obstruction (blockage) of the bile duct, emphysema of the gallbladder (distension of the gallbladder by gases formed in it), intestinal obstruction.

Release form. Tablets, soluble in the intestine, containing 0.192 g of pancreatin, 0.05 g of hemicillulase and 0.025 g of bovine bile extract, in a package of 100 pieces.

Storage conditions. In a dry place.

Prolipase

Pharmachologic effect. The drug contains pancreatic (secreted by the pancreas) enzymes. Normalizes digestion.

Indications for use. Exocrine insufficiency (insufficient secretion of digestive juices) of the pancreas, stomach, liver, gallbladder; flatulence (accumulation of gas in the intestines); diarrhea (diarrhea) of a non-infectious nature; violation of chewing function.

Method of administration and dosage. Inside, 1-2 capsules (without chewing) during meals and 1 capsule in between meals.

Side effect. Allergic reactions, diarrhea, hyperuricosuria (increased excretion of uric acid in the urine).

Contraindications. Hypersensitivity to the drug.

Release form. Capsules in a package of 100 pieces. 1 capsule contains pancreatic enzymes with lipase activity of 4000 ME, amylase of 2000 ME and protease of 25,000 ME.

Storage conditions. Store in a cool dry place.

TAGESTAL (Tagestalum)

Pharmachologic effect. A complex preparation containing pancreatin, hemicellulase and bovine bile extract. Normalizes digestion.

Indications for use. Digestive disorders associated with diseases of the pancreas, gallbladder, liver, heavy consumption of fatty foods, gastroenteritis (inflammation of the mucous membranes of the stomach and small intestine), to remove gases before radiological and ultrasound examinations.

Method of administration and dosage. Inside during or immediately after meals, 1-2 tablets 3 times a day; before X-ray radiological procedures, take 2 tablets 2-3 times a day for 2-3 days.

Side effect. Allergic reactions.

Contraindications. Hypersensitivity to the drug, severe liver dysfunction, high levels of bilirubin (bile pigment).

Release form. Dragee containing 0.192 mg of pancreatin, 0.05 g of hemicellulase and 0.025 g of bovine bile extract, in a package of 100 pieces.

Storage conditions. Store in a cool dry place.

TRIFERMENT (Trifermentum)

Pharmachologic effect. A drug containing the enzymes trypsin, lipase and amylase. Replenishes the deficiency of digestive enzymes in the body.

Indications for use. Lack of secretory (secretion of digestive juices) and digestive capacity of the stomach and intestines (chronic gastritis - inflammation of the stomach, colitis - inflammation of the colon), chronic pancreatitis (inflammation of the pancreas), hepatitis (inflammation of the liver tissue), cholecystitis (inflammation of the gallbladder).

Method of administration and dosage. Inside before meals for adults, 1-3 tablets a day; children 1-2 tablets a day.

Side effects and contraindications are the same as for pangrol 400.

Release form. Coated dragee, pack of 30. 1 tablet contains trypsin 18 IU, lipase 6 IU, amylase (1:10).

Storage conditions. In a dry, dark place.

FESTAL (Festal)

Synonyms: Digestal.

Pharmachologic effect. A preparation of standardized pancreatic (secreted by the pancreas) enzymes (lipase, amylase, protease), hemicellulase and dried bovine bile. Promotes the breakdown and assimilation of foods containing fats, proteins, carbohydrates and plant ballast substances (hemicellulase).

Indications for use. Relative or absolute secretory pancreatic insufficiency (insufficient secretion of digestive enzymes by the pancreas) of various etiology (causes); flatulence (accumulation of gas in the intestines) due to cholecystitis (inflammation of the gallbladder); aeration of the intestines (cleansing) before the X-ray; gastrointestinal disorders (gastrointestinal disturbances) resulting from treatment with para-aminosalicylic acid and broad-spectrum antibiotics

actions, damage to the chewing apparatus; failure of digestion in old age.

Method of administration and dosage. Inside, 1-2 pills during or after meals 3 times a day.

Contraindications. Hepatitis (inflammation of the liver tissue), obstructive jaundice (jaundice caused by a blockage in the bile ducts).

Release form. Dragee containing pancreatin 0.02 g, bile extract of cattle 0.025 g and hemicellulase 0.05 mg, in a package of 30 pieces and 100 pieces.

Storage conditions. In a cool, dry place, protected from light.

ENZYSTAL (Enzystalum)

Pharmachologic effect. An enzyme preparation containing pancreatin, hemicellulase and bile components. Normalizes digestion.

Indications for use. Lack of exocrine function (secretion of digestive juices) of the pancreas, stomach, intestines, liver; flatulence (accumulation of gas in the intestines); diarrhea (diarrhea) of a non-infectious nature; to improve digestion in persons with normal function of the gastrointestinal tract with disorders of the chewing apparatus, sedentary lifestyle, prolonged immobilization (immobilization); preparation for X-ray and ultrasound examinations of the abdominal organs.

Method of administration and dosage. Inside, 1-2 pills 3 times a day during or after meals for weeks, months and even years.

Side effect. Nausea, diarrhea.

Contraindications. Hepatitis (inflammation of the liver tissue), obstructive jaundice (jaundice caused by blockage of the biliary tract), intestinal obstruction, hypersensitivity to the drug.

Release form. Dragee containing 0.192 g of pancreatin, 0.05 g of hemicellulase and 0.025 g of bile components, in a package of 10 pieces.

Storage conditions. In a dry, dark place.

Pancreatin is also a part of the preparations vigeratin, mexase, pancreoflet.

Pepsinum

Indications for use. With digestive disorders (achilia, lack of secretion in the stomach of hydrochloric acid and enzymes, hypo- and anacid gastritis - inflammation of the stomach, accompanied by a decrease in the level or absence of hydrochloric acid, dyspepsia - indigestion, etc.).

Method of administration and dosage. Inside, before or during meals, 0.2-0.5 g (children from 0.05 to 0.3 g) 2-3 times a day in powder or in 1-3% solution of diluted hydrochloric acid.

Release form. Powder.

Storage conditions. In a cool, dark place.

ACIDIN-PEPSIN (Acidin-pepsinum)

Synonyms: Betacid, Atsipepsol, Pepsamin.

Pharmachologic effect. Combined drug. Promotes the digestion of food in the stomach.

Indications for use. With hypo- and anacid gastritis (inflammation of the stomach, accompanied by a decrease in the level or absence of hydrochloric acid), achilia (no secretion of hydrochloric acid and enzymes in the stomach), dyspepsia (digestive disorders).

Method of administration and dosage. Inside during or after meals in "/ 4 -" / 2 glasses of water, 1-2 tablets 3-4 times a day; children (depending on age) from 1/4 tablet to 1 tablet 3-4 times a day.

Release form. Tablets of 0.25 g in a package of 50 pieces. Ingredients: pepsin - 1 part, betaine hydrochloride - 4 parts.

Storage conditions. Regular.

PEPSIDIL (Pepsidilum)

A solution in hydrochloric acid of the products of enzymatic hydrolysis (decomposition with the participation of water, catalyzed / accelerated / by an enzyme) of the tissue of the gastric mucosa of pigs, containing all the components of the secretion of the gastric glands (gastric juice).

Pharmachologic effect. Pepsin - the main therapeutic factor of the drug - determines the digestion of proteins in the stomach.

Indications for use. Hypacid and anacid gastritis (inflammation of the stomach, accompanied by a decrease in the level or absence of hydrochloric acid).

Method of administration and dosage. Inside during meals, 1-2 tablespoons (preferably through a tube) 3 times a day.

Release form. Available in 450 ml bottles.

Storage conditions. At a temperature of +4 "C.

PLANTEX (Plantex)

Pharmachologic effect. A preparation containing herbal ingredients for the correction of digestive disorders in children. The fruits and essential oil of fennel, which are part of the plantex, have a stimulating digestion and carminative effect. Stimulates digestion by increasing the secretion of gastric juice and peristalsis (undulating bowel movements). The drug prevents flatulence in the intestines and enhances the elimination of gases and, thus, relieves spasms caused by intestinal flatulence (accumulation of gas in the intestines).

Indications for use. Correction of digestive disorders in children, including infants.

Method of administration and dosage. For infants, pour the contents of a sachet (5 g) into a baby bottle for feeding, add 100 ml of freshly boiled water or milk and shake until the tea dissolves. Cool to room temperature before use.

For children over 1 year old, pour 1-2 bags (5-10 g) of tea into a cup containing 100-150 ml of boiled warm or cold water and stir to dissolve. The tea is not sweetened.

Side effect. In rare cases, hypersensitivity reactions are possible.

Contraindications. Hypersensitivity to drug components.

Release form. Dry substance for making tea in bags of 5 g. 1 bag contains: extract of fruits of fennel - 2.75 g, fennel perfume with 16% essential oil - 0.015 g, glucose - 2.5 g, lactose - 2.235 g. The calorie content of tea (prepared from one bag) is 19 kcal.

Storage conditions. In a dry place.

SOLIZIM (Solizymum)

Lipolytic (decomposing fats) enzyme preparation obtained from the culture of Penicillium solitum.

Pharmachologic effect. Hydrolyzes (decomposes with the participation of water) vegetable and animal fats; promotes the digestion and absorption of fats.

Indications for use. Chronic pancreatitis (inflammation of the pancreas) with a decrease in lipolytic activity; chronic diseases of the gastrointestinal tract: gastritis (inflammation of the stomach), hepatitis (inflammation of the liver tissue), cholecystitis (inflammation of the gallbladder), enteritis (inflammation of the small intestine), enterocolitis (inflammation of the small and large intestine); after operations on the pancreas, intestines, gallbladder.

Method of administration and dosage. Inside, during or immediately after a meal, 40,000 LU (lipolytic units) 3 times a day. The daily dose is 120,000 LE. The course of treatment is 2-4 weeks.

Release form. Tablets of 20,000 LU, soluble in the intestine, in a package of 50 pieces.

Storage conditions. In a dry, dark place at a temperature not exceeding +4 ° C.

SOMILASE (Somilasum)

Combined preparation containing solizyme (lipolytic / fat-decomposing / enzyme derived from Penicilium solutum culture liquid) and alpha-amylase derived from aminosubtilin.

Pharmachologic effect. Hydrolyzes (decomposes with the participation of water) vegetable and animal fats and breaks down polysaccharides, as a result, the enzymatic insufficiency of digestion is compensated.

Indications for use. Insufficiency of pancreatic function, leading to a decrease in lipolytic and amylalytic activity (the ability to decompose fats and polysaccharides) of the duodenal contents (contents of the duodenum) in chronic pancreatitis (inflammation of the pancreas); failure of digestion: gastritis (inflammation of the stomach), enteritis (inflammation of the small intestine), enterocolitis (inflammation of the small and large intestine), hepatitis (inflammation of the liver tissue), cholecystitis (inflammation of the gallbladder); after operations on the pancreas, intestines, liver, stomach; with functional disorders associated with diet.

Method of administration and dosage. Inside during meals or immediately after meals, 1-2 tablets 3 times a day (the tablet is swallowed whole, without chewing) daily.

Side effects and contraindications have not been identified.

Release form. Intestinal-soluble tablets containing 20,000 LE (0.0286 g) of solizime and 300 U (0.1363 g) of alpha-amylase, in a package of 50 pieces.

Storage conditions. In a dry, dark place at a temperature not higher than +5 ° С, not lower than 0 ° С.

UNIENSYM (Unienzymum)

Pharmachologic effect. Normalizes digestion. It has an adsorbing (absorbing) effect.

Indications for use. Digestive disorders, flatulence (accumulation of gas in the intestines).

Method of administration and dosage. Inside, 1-2 tablets, without chewing, during or immediately after a meal.

Side effects and contraindications have not been identified.

Release form. Film-coated tablets in packs of 30 and 100 pieces. 1 tablet contains: diastases - 0.02 g, papain - 0.03 g, simethicone - 0.05 g, nicotinamide (vit.RR) - 0.025 g and activated carbon - 0.075 g.

Storage conditions. In a dark place.

Enzymes (synonym: enzymes) of the digestive system are protein catalysts,which are produced by the digestive glands andbreak down food nutrients into simpler components during digestion.

Enzymes (lat.), They are also enzymes (Greek), are divided into 6 main classes.

The enzymes that work in the body can also be divided into several groups:

1. Metabolic enzymes - catalyze almost all biochemical reactions in the body at the cellular level. Their set is specific for each type of cells. The two most important metabolic enzymes are 1) superoxide dismutase (SOD), 2) catalase. FROMuperoxide dismutase protects cells from oxidation.Catalase decomposes hydrogen peroxide, which is dangerous for the body, which is formed in the process of metabolism, into oxygen and water.

2. Digestive enzymes - catalyze the breakdown of complex nutrients (proteins, fats, carbohydrates, nucleic acids) into simpler components. These enzymes are produced and act in the digestive system of the body.

3. Food enzymes - enter the body with food. It is curious that some food products provide for a fermentation stage during their production, during which they are saturated with active enzymes. Microbiological processing of food products also enriches them with microbial enzymes. Of course, the presence of ready-made additional enzymes facilitates the digestion of such products in the gastrointestinal tract.

4. Pharmacological enzymes - are introduced into the body in the form drugs in medical or preventive purposes... Digestive enzymes are one of the most commonly used groups of drugs in gastroenterology. The main indication for the use of enzyme agents is the state of impaired digestion and absorption of nutrients - maldigestion / malabsorption syndrome. This syndrome has a complex pathogenesis and can develop under the influence of various processes at the level of secretion of individual digestive glands, intraluminal digestion in the gastrointestinal tract (GIT) or absorption. The most common causes of disorders of digestion and absorption of food in the practice of a gastroenterologist are chronic gastritis with reduced acid-forming function of the stomach, post-gastro-resection disorders, cholelithiasis and biliary dyskinesia, exocrine pancreatic insufficiency. Currently, the global pharmaceutical industry produces a large number of enzyme preparations, which differ from each other both in the dose of digestive enzymes they contain and in various additives. Enzyme preparations are available in various forms - in the form of tablets, powder or capsules. All enzyme preparations can be divided into three large groups: tablet preparations containing pancreatin or digestive enzymes of plant origin; preparations that include, in addition to pancreatin, bile components, and preparations produced in the form of capsules containing enteric-coated microgranules. Sometimes the enzyme preparations include adsorbents (simethicone or dimethicone), which reduce the severity of flatulence.

Digestive enzyme groups

• Proteolytic (proteases, peptidases) - they break down proteins into short peptides or amino acids.
  
• Lipolytic (lipases) - break down fats to glycerol and fatty acids.
  
• Amylolytic (amylases, carbohydrases) - break down polysaccharides (starch) to simpler sugars (disaccharides or monosaccharides).
  
• Nucleases - cleaves nucleic acids to nucleotides.

Gastrointestinal tract (gastrointestinal) enzymes table

Digestive tract department	Enzyme	Substrate	Product	Optimal environment
Oral cavity	Amylase (synonyms: ptyalin, diastase, α-amylase, EC 3.2.1.1; 1,4-α-D-glucan glucanohydrolase; glycogenase; glycosyl hydrolase)	Starch. Target: α-1,4-glycosidic bonds between monomers.	Oligosaccharides, maltose (malt sugar, glucose disaccharide)	Weakly alkaline. pH 6.7-7.0.Ions Ca 2+
	Maltase (acidic α-glucosidase)	Maltose (malt sugar)	Glucose
	All major gastrointestinal enzymes in trace amounts
Esophagus	Does not release its own enzymes, it continues the effect of saliva enzymes on food
Stomach	Refers to hydrolases and, in particular, to endopeptidases, i.e. it cleaves the central peptide bonds in protein and peptide molecules. Has 12 different isoforms.	Proteins. Primary targets: tyrosine-phenylalanine aromatic amino acid bonds	Peptides(peptones), free amino acids	Sour. pH 1.9. For isoforms: 2.1-3.9
	Chymosin (rennet)	Milk proteins (caseinogen)		Sour, Ca ions 2+
	Gelatinase (pepsin B, parapepsin I)	Proteins: collagen, elastin		Sour. pH 2.1.
	Lipase (gastric)	Emulsified fats	Glycerin + fatty acids	Sour
	Ureaza	Urea	Ammonia + CO 2	Alkaline. pH 8.0
Duodenal ulcer (duodenal intestine)	Lipase (steapsin)	Fats (lipids). With the help of bile, it digests fats and fatty acids, as well as fat-soluble vitamins A, D, E, K.	Glycerin + fatty acids	Alkaline
	Trypsin	Proteins and peptides. Main targets: bonds between the residues of the positively charged amino acids lysine and arginine. Converts hydrolase enzymes into active enzymes. It also digests itself. Also catalyzes the hydrolysis of waxes - esters.	Amino acids	Alkaline. pH 7.8-8.
	Chymotrypsin
	Amylase	Starch	Maltose (malt sugar)
	Enteropeptidase (enterokinase from the group of endopeptidases, peptide hydrolase) - an important auxiliaryan enzyme that does not digest food	Trypsinogen. Enteropeptidase converts the inactive pancreatic enzyme trypsinogen to active trypsin.	Trypsin.	Alkaline.
Small intestine	Erepsin	Protein		Alkaline.
	Alanine aminopeptidase (AAP) Refers to endopeptidases, because cleaves the N-terminal amino acid in the peptide molecule.	Peptides resulting from the breakdown of proteins in the stomach and duodenum.	Proline containing amino acids and dipeptides (X-Pro species)	Alkaline.
	Lipase	Fatty acid		Alkaline.
	Maltase (acidic α-glucosidase)	Maltose (malt sugar)	Glucose	Alkaline.
	Isomaltase	Maltose and Isomaltose	Glucose	Alkaline.
	Suharase	Sucrose (beet or cane sugar)	Glucose + Fructose	Alkaline.
	Lactase	Lactose (milk sugar)	Glucose + Galactose	Alkaline.
	Nuclease	Nucleic acids	Nucleotides
Colon	Enzymes of microorganisms that make up the colon microbiota

Abdominal discomfort and digestive disorders have happened to each of us. There may be several sources of such problems.

To prevent unpleasant consequences, it is necessary to add special preparations to the diet to improve digestion. They were created to quickly and effectively eliminate disorders of the digestive tract.

Signs you need pills to improve digestion

With regular examination of the body, any malfunction in its work will be instantly detected and corrected. When problems relate to the gastrointestinal tract, they provoke the appearance of a number of symptoms that can be used to diagnose the disease on early stages... We list the main signs in which it is necessary to take a remedy to improve digestion.

• Chronic fatigue and depression... Similar symptoms appear from a lack of vitamins, minerals and nutrients in the body. With a shortage of important components, he is forced to deplete his own reserves, which are either slowly or not at all replenished.
• Increased sleepiness... Appears with a deficiency of important substances in the usual diet.
• Deterioration of the skin condition.The skin becomes dry, unpleasant to the touch, scars and age spots appear.
• Deterioration of hair and nails. One of the most common and dangerous symptoms of a lack of beneficial nutrients in the body.
• Discomfort in the intestines. Regular constipation, diarrhea, flatulence and nausea are clear signs of gastrointestinal disturbances.
• Stomach pain. If your stomach often hurts and twists, especially after eating food, then you should immediately contact a qualified specialist.
• Loss of appetite. This symptom is a logical consequence of the previous one, and denotes the rapid development of the disease.

If you notice one of the above signs in yourself, then you need to go to a doctor's consultation and purchase medicines to improve digestion.

For what reasons is digestion disturbed?

Indigestion can begin after a hearty dinner or, on the contrary, prolonged malnutrition. Diet directly affects the functioning of the digestive system, so you should be careful about eating food.

Unhealthy food abuse... A large amount of smoked, salted and fried foods makes digestive system work in excess of the norm, which over time will irreversibly lead to the appearance of failures.

Overeating... Experts say that a meal should be finished with a feeling of slight hunger. The fact is that the connection between the stomach and the brain does not differ at lightning speed. For this reason, people often overeat, as they continue to eat when the stomach is already full of food. To eliminate these risks, you should eat slowly and in moderation.

Not chewing food enough... Rapid eating is fraught with unpleasant consequences. Especially when it comes to solid foods that need additional chewing before entering the stomach.

Late supper... After 8 o'clock in the evening, the body's working capacity decreases markedly, and with it the ability to digest heavy food.

Drinking water with food... A person needs to consume a large amount of water every day, but not while eating. By drinking water with food, you slow down the digestion process and partially destroy beneficial features digestible products.

Sticking to simple rules healthy eating, you will significantly reduce the risk of stomach discomfort and problems with the digestive system. But for those who have already faced similar difficulties, we present a list of worthy remedies for improving digestion.

The best drugs to improve digestion

Disorders in the digestive system should be eliminated with a proper diet and special medicines... Drugs that improve digestion and bowel function are divided into 3 types according to the key active substance:

• Pancreatin-based medicines. Pancreatin is considered the most efficient and fastest-acting digestive enzyme. Within a few minutes after taking such medicines, the substance begins to actively act and fight the signs of indigestion.
• Medicines based on pancreatin in alliance with other additional elements (bile acids, cellulose, etc.). Auxiliary components accelerate the breakdown of complex sugar compounds, contribute to the normalization of intestinal function and increase the secretion of digestive enzymes.
• Medicines whose action is aimed at restoring the normal functioning of the pancreas.

Important!Only a qualified doctor can determine the drug from which group is able to solve your stomach problems. Sometimes pain symptoms similar in action can occur from different diseases. Therefore, in some cases, it is more advisable to choose a drug that includes additional elements than conventional Pancreatin.

The rate at which the drug affects the source of the problem also depends on the form of its release. In modern medicine, two options for the release of digestive enzymes are common:

Capsules.Enzymatic preparations for improving digestion in capsule form are produced relatively recently. But their effectiveness has already been repeatedly proven in clinical studies. The advantage of capsules over the tablet form lies in the simultaneous effect on the stomach and intestines. Due to the special shell, part of the active substance is distributed in the stomach, and the rest goes directly to the intestine.

Pills.This is a more common form of drug release. In this connection, buyers initially develop a loyal attitude towards drugs in the form of pills. As noted earlier, the effect of the tablets is directed only to the functioning of the stomach.

The choice of the form of release of the drug should be based on the doctor's recommendations. There is no need to overpay money for capsules if the source of discomfort is located directly in the stomach. An experienced specialist will be able to determine the cause of the disease and suggest an optimal and effective solution.

Below is a list of the most popular and effective drugs that improve digestion.

Pancreatin

Pancreatin is considered one of the most effective drugs for digestion. Its popularity is due not only to its strong action, but also to a rather modest price. The use of Pancreatin is prescribed in the following situations:

• with inadequate secretion of pancreatic enzymes;
• with prolonged disturbances in the work of the stomach, intestines or liver;
• when consuming a large amount of food;
• when leading an inactive lifestyle;
• with problems with chewing processes.

The drug has no optimal dosages. However, it is considered normal to take one tablet with each meal. In acute diseases, it is recommended to increase the dosage to 2-3 tablets. Pancreatin has practically no side effects... Any consequences after taking the drug are observed in only 1% of all users. The main "side effects" include:

• discomfort in the stomach, nausea, vomiting;
• allergic reactions, in the form of a skin rash;
• an increase in the amount of uric acid in the body.

Despite the rare occurrence of side effects from taking the drug, Pancreatin is recommended to be used exclusively on the recommendation of a doctor. The specialist will be able to determine the optimal dosage and frequency of doses.

Creon

Many gastroenterologists prefer Creon. The fact is that it is available in capsules, which significantly increases its effectiveness. The key active ingredient of the drug is pancreatin, which stimulates the production of vital digestive enzymes. Creon is necessary for:

• treatment of chronic pancreatitis;
• conducting postoperative therapy on the digestive tract;
• oncological diseases (if the tumor interferes with the normal functioning of the stomach or pancreas);
• eating a large amount of food (at holidays, feasts, etc.).

There are practically no side effects of the drug, occasionally there are cases of diarrhea or mild pain in the abdomen. Most often, these negative consequences are not caused by pancreatin, but by additional elements that make up Creon.

Mezim

Mezim can rightfully be called the most popular drug that improves the functioning of the digestive system. This is due not only to a powerful advertising campaign in the media, but also to the high efficiency of the drug. The composition of one Mezim tablet includes pancreatin, lipase, amylase and protease. The drug is prescribed in the following situations:

• with a decrease in the amount of digestive enzymes produced;
• if you have problems with metabolism;
• in the event of inflammatory processes on the walls of the gastric mucosa;
• with chronic pancreatitis.

Experts advise drinking 1 tablet before meals. In some cases, increased dosages are prescribed. The course of treatment can last from a week to 3-4 months, depending on the stage of the disease.

Important!Mezim is contraindicated in people suffering from intestinal obstruction, jaundice or hepatitis.

The composition of Mezim is identical to that of Pancreatin, but the difference lies in the shell. Mezim has a sweeter and more palatable coating that attracts most patients. Also, because of this feature, Mezim is more often prescribed to children.

Festal

Festal is an enzymatic agent, whose composition includes, in addition to pancreatin, hemicellulose with an extract from the bovine gallbladder. Hemicellulose promotes the absorption of fiber, and bovine bile extract activates lipase, which, in turn, normalizes the absorption of fats and other nutrients. All components interact harmoniously and do not contradict each other. Thanks to this, Festal has a high speed of action and a strong effect.

The drug is taken when:

• insufficient amount of pancreatic enzymes;
• diarrhea unless it is caused infection intestines;
• flatulence;
• the presence of irritations on the intestinal walls;
• abundant use of "harmful" food (spicy, salty, fatty foods).

• the presence of pancreatitis in the acute stage;
• jaundice;
• hepatitis;
• intestinal obstruction;
• allergic reactions caused by certain ingredients of the medicine;
• diabetes mellitus (since the composition of the drug shell contains glucose and sucrose).

You can buy Festal at any pharmacy kiosk. Average price for a medicine: 150-200 rubles.

Enzistal

An effective remedy that helps to forget about disturbances in the digestive tract forever. The composition of the preparation contains pancreatin, hemicellulose and bile components. Additional elements enhance the overall effect and cover a large area of \u200b\u200bdisease. Enzistal should be taken when:

• lack of digestive enzymes in the body;
• developing flatulence;
• disorders of chewing processes, which are often found in people with prosthetic teeth, as well as in people with damaged jaws or gums;
• inactive lifestyle.

Reception of Enzistal should be limited or carried out under close medical supervision if the patient suffers from:

• renal or hepatic impairment;
• jaundice;
• intestinal obstruction.

In the presence of such contraindications, taking the drug can cause unpleasant consequences. As for the side effects, Enzistal does not have many of them, but they are all serious:

• allergic processes, in the form of skin rash and lacrimation;
• discomfort in the stomach area;
• nausea;
• diarrhea;
• irritation on the walls of the mucous membrane.

The presence of the above-described side effects is a significant reason for the immediate suspension of treatment. In other cases, Enzistal is characterized as an incredibly effective and relatively inexpensive remedy for combating gastrointestinal problems.

Somilaza

Somilase belongs to a number of drugs that have a positive effect not only on the digestive system, but also on the pancreas. The preparation contains solizim, a food enzyme that takes an active part in the process of lipase of adipose tissues. Due to the universal effect, the mechanism of action of the drug is somewhat different from the above-mentioned drugs. However, Somilaza is not inferior in efficiency. The microelements of the preparation break down the assimilated vegetable and animal fats, replenishing at their expense the deficiencies of digestive enzymes. Somilase is prescribed for:

• digestive disorders;
• chronic pancreatitis;
• acute gastritis;
• the occurrence of inflammatory processes in the small or large intestine;
• having problems with gallbladder or liver;
• recovery after surgery in the stomach, liver or pancreas.

Somilaza has no serious contraindications, except in cases where the patient has an individual intolerance to specific ingredients of the drug. For this reason, Somilaza is very popular and is often prescribed by doctors.

Important!Somilaza makes adjustments to the work of the pancreas, therefore, before starting the use, it is imperative to consult a doctor.

Conclusion

Digestive medications are some of the most popular products in drugstores. This is due to the fact that most people do not adhere to the principles proper nutrition... If you feel the same way, then one of the above drugs will help your stomach function normally and avoid possible diseases.

pancreatin is the most affordable and good drug... Mezim has a price in comparison with him wow! but it works the same way.

I have tried many pills for digestive problems, due to my incontinence in food, I have to drink pills to improve stomach function, but sometimes I need help urgently on the road, with heaviness or heartburn, Antareit helps me, because I do not need to drink it, but only suck small sweet tablets.

Oleg, yes, I perceive all these medicines only as emergency help, in no case for permanent use.
I used to have some kind of digestive problems. I went to the doctors, but they found nothing serious. Nausea after eating very often bothered. But there was definitely no pregnancy.
A friend advised me drops of gastroguttal on plant based... You can drink them without fear. And most importantly, they help a lot.